Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pediatric midline H3K27M-mutant tumor with disseminated leptomeningeal disease and glioneuronal features: case report and literature review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Jul 2021

Navarro Ralph E, Golub Danielle, Hill Travis, McQuinn Michelle W, William Christopher, Zagzag David, Hidalgo Eveline Teresa

Abstract excerpt

BACKGROUND: H3K27M-mutant midline lesions were recently reclassified by the World Health Organization (WHO) as "diffuse midline glioma" (DMG) based entirely on their molecular signature. DMG is one of the most common and most lethal pediatric brain tumors; terminal progression is typically caused by local midbrain or brainstem progression, or secondary leptomeningeal dissemination. H3K27M mutations have also been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Magnetic Resonance Imaging

Share to Meningeal Neoplasms

Share to Mutation

Source

Identifiers

PMID: 32989496
DOI: 10.1007/s00381-020-04892-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pediatric midline H3K27M-mutant tumor with disseminated leptomeningeal disease and glioneuronal features: case report and literature review.PMID 32989496Read ↗

Pediatric spinal cord diffuse midline glioma, H3 K27-altered with intracranial and spinal leptomeningeal spread: A case report.Semantic proximity Read ↗

An Emerging Pediatric CNS Tumor: Imaging Evaluation of H3K27M and BRAF V600E Comutated Midline Tumors.Semantic proximity Read ↗

Imaging Characteristics of Pediatric Diffuse Midline Gliomas with Histone H3 K27M Mutation.Semantic proximity Read ↗

Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adultsSemantic proximity Read ↗

Paediatric diffuse leptomeningeal tumor with glial and neuronal differentiation harbouring chromosome 1p/19q co-deletion and H3.3 K27M mutation: unusual molecular profile and its therapeutic implications.Semantic proximity Read ↗

Diffuse midline glioma H3 K27M-mutant in adults: A report of six cases and literature review.Semantic proximity Read ↗

Adult diffuse midline gliomas: Clinical, radiological, and genetic characteristics.Semantic proximity Read ↗

Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations.Semantic proximity Read ↗

Diffuse midline gliomas with histone H3-K27M mutation: A rare case with PNET-like appearance and neuropil-like islands.Semantic proximity Read ↗

Histone-mutant glioma presenting as diffuse leptomeningeal disease.Semantic proximity Read ↗

Extending the Neuroanatomic Territory of Diffuse Midline Glioma, K27M Mutant: Pineal Region Origin.Semantic proximity Read ↗

[Clinical Findings of Thalamic and Brainstem Glioma Including Diffuse Midline Glioma, H3K27M Mutant:A Clinical Study].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.