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Article

Introduction of a single-nucleotide variant, rs16851030, into the ADORA1 gene increased cellular susceptibility to hypoxia.

Personalized medicine - 1 Jan 2024

Wong Poh Kuan, Syafruddin Saiful Effendi, Cheah Fook Choe, Azmi Norazrina, Ng Pei Yuen, Chua Eng Wee

Abstract excerpt

Aim: Rs16851030, a single-nucleotide variant located in the 3'-untranslated region of the ADORA1 gene, has been proposed as a potential marker of caffeine sensitivity in apnea of prematurity. Besides, it is associated with aspirin-induced asthma and the development of acute chest syndrome. However, its functional significance is still unconfirmed. This study aimed to elucidate the functional impact of rs16851030...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39440484
DOI: 10.1080/17410541.2024.2412514

Genes

ADORA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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