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Study on molecular mechanism of intervertebral disc degeneration by single cell hdWGCNA combined with transcriptome sequencing

3 Sept 2024

Abstract excerpt

Background: Intervertebral disc degeneration (IVDD) is one of the important causes of lower back pain, seriously affecting people's health and quality of life. This research employs single-cell analysis to identify the specific cellular subtypes and key regulatory genes associated with IVDD. Methods: We analyzed the single-cell data and screened cells that closely associated with the development of IVDD. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39430607
DOI: 10.1016/j.ncrna.2024.09.003

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