Article
Integration of single-cell and transcriptome sequencing data reveals the mechanism of macrophage polarization-related genes in intervertebral disc degeneration
2026-07-14
Abstract excerpt
<title>Abstract</title> <p> <bold>Introduction</bold> : Intervertebral disc degeneration (IVDD) is a major contributor to low back pain, profoundly affecting the quality of life for patients. The polarization of macrophages may play a crucial role in the mechanism of IVDD. Therefore, investigating the biological roles of related genes in IVDD provided new insights into its treatment. <bold>Methods</bold> : Th...
Topics
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- Cervical and Thoracic Myelopathy
- Inflammatory mediators and NSAID effects
- Macrophage Migration Inhibitory Factor
- Musculoskeletal pain and rehabilitation
- Osteoarthritis Treatment and Mechanisms
- Scoliosis diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Spondyloarthritis Studies and Treatments
Identifiers and source
- Literature Corpus work
- 9bfeb07f-8b54-5f10-ba6f-081ca6b9ae02
- DOI
- 10.21203/rs.3.rs-10182228/v1
