Role of patatin-like phospholipase domain-containing 3 gene for decreasing kidney function in recently diagnosed diabetes mellitus.

doi:10.1016/j.dsx.2024.103137

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Article

Role of patatin-like phospholipase domain-containing 3 gene for decreasing kidney function in recently diagnosed diabetes mellitus.

Diabetes & metabolic syndrome - 1 Oct 2024

Zaharia Oana Patricia, Strassburger Klaus, Knebel Birgit, Binsch Christian, Kupriyanova Yuliya, Möser Clara, Bódis Kálmán, Prystupa Katsiaryna, Yurchenko Iryna, Mendez Cardenas Dania Marel, Schön Martin, Herder Christian, Al-Hasani Hadi, Schrauwen-Hinderling Vera, Jandeleit-Dahm Karin, Wagner Robert, Roden Michael

Abstract excerpt

AIMS: We examined the association of the G allele in the single-nucleotide polymorphism (SNP) rs738409 in the third exon of patatin-like phospholipase domain-containing 3 gene (PNPLA3) gene, with chronic kidney disease in diabetes endotypes. METHODS: Participants with recent-onset diabetes (n = 707) from the prospective German Diabetes Study (GDS) underwent cluster assignment, detailed phenotyping, genotyping and...

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PMID: 39427597
DOI: 10.1016/j.dsx.2024.103137

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