PNPLA3 variation and kidney disease.

doi:10.1111/liv.16010

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Article

PNPLA3 variation and kidney disease.

Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2025

Mantovani Alessandro, Targher Giovanni

Abstract excerpt

Accumulating epidemiological evidence shows that the patatin-like phospholipase domain-containing protein-3 (PNPLA3) rs738409 G allele, which is the most robust genetic variant associated with greater susceptibility to metabolic dysfunction-associated steatotic liver disease (MASLD), is significantly associated with impaired kidney function in both adults and children, regardless of the presence of common renal...

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Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Renal Insufficiency, Chronic

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Share to Acyltransferases

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Share to Phospholipases A2, Calcium-Independent

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Identifiers

PMID: 38873992
DOI: 10.1111/liv.16010

Genes

PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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PNPLA3 variation and kidney disease.PMID 38873992Read ↗

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