Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.

Frontiers in immunology - 1 Jan 2024

Lu Guojun, Liu Hongliang, Wang Huilin, Tang Xiaozhun, Luo Sheng, Du Mulong, Christiani David C, Wei Qingyi

Abstract excerpt

Background: T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. Lung cancer has the highest mortality among all cancers. However, the roles of genetic variants of the T cell exhaustion-related genes in the prognosis of non-small cell lung cancer (NSCLC) patients has not been reported. Methods: We conducted a two-stage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 2',5'-Oligoadenylate Synthetase
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokines, CC

Share to Genome-Wide Association Study

Share to Lung Neoplasms

Share to Prognosis

Share to Quantitative Trait Loci

Share to T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 39416786
DOI: 10.3389/fimmu.2024.1455927
PMCID: PMC11479925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.PMID 39416786Read ↗

Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer.Semantic proximity Read ↗

Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer.Semantic proximity Read ↗

Potentially functional variants of INPP5D and EXOSC3 in immunity B cell-related genes are associated with non-small cell lung cancer survival.Semantic proximity Read ↗

Analysis of PD1, LAG3, TIGIT, and TIM3 expression in human lung adenocarcinoma reveals a 25-gene signature predicting immunotherapy responseSemantic proximity Read ↗

Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers.Semantic proximity Read ↗

Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study.Semantic proximity Read ↗

Machine Learning Study of SNPs in Noncoding Regions to Predict Non-small Cell Lung Cancer Susceptibility.Semantic proximity Read ↗

Exome-Wide Association Study Identifies Low-Frequency Coding Variants in 2p23.2 and 7p11.2 Associated with Survival of Non-Small Cell Lung Cancer Patients.Semantic proximity Read ↗

Polymorphisms of key chemokine genes and survival of non-small cell lung cancer in Chinese.Semantic proximity Read ↗

Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival.Semantic proximity Read ↗

Systematic evaluation of genetic variants in three biological pathways on patient survival in low-stage non-small cell lung cancer.Semantic proximity Read ↗

Potentially functional variants of ERAP1, PSMF1 and NCF2 in the MHC-I-related pathway predict non-small cell lung cancer survival.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.