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Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer.

Journal for immunotherapy of cancer - 1 Aug 2020

Wang Qinchuan, Gu Jianchun, Wang Linbo, Chang David W, Ye Yuanqing, Huang Maosheng, Roth Jack A, Wu Xifeng

Abstract excerpt

BACKGROUND: Recent advances in T cell-related immunotherapy have brought remarkable progress in the treatment of non-small cell lung cancer (NSCLC). However, whether and how genetic variations of T cell cancer immune response genes can influence clinical outcomes of NSCLC patients remain obscure. METHODS: In this multiphase study, we assessed 2450 single-nucleotide polymorphisms (SNPs) from 280 T cell cancer...

Topics

Aged
Humans
Lung Neoplasms
Neoplasm Staging
Phenotype
Polymorphism, Single Nucleotide
T-Lymphocytes
Treatment Outcome

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32764075
DOI: 10.1136/jitc-2019-000336
PMCID: PMC7412613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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