Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation strongly affects the inhibition of human carbonic anhydrase I CO2 hydration activity.

Archives of biochemistry and biophysics - 1 Nov 2024

Angeli Andrea, De Luca Vivian, Huang Xiaojing, Winter Daniel L, Capasso Clemente, Supuran Claudiu T, Donald William A

Abstract excerpt

Human carbonic anhydrases (hCAs) have essential roles in respiration, acid-base balance, and fluid secretion, with implications in diseases such as glaucoma, epilepsy, obesity, and cancer. Of the fifteen known hCAs, human CA I (hCA I) is particularly abundant in erythrocytes, playing a critical role in CO2 transport. Despite extensive research on hCA I, the impact of post-translational modifications (PTMs),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbon Dioxide
Share to Kinetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Phosphorylation

Share to Sulfonamides

Source

Identifiers

PMID: 39413948
DOI: 10.1016/j.abb.2024.110182

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation strongly affects the inhibition of human carbonic anhydrase I CO2 hydration activity.PMID 39413948Read ↗

Structural Characterization of Carbonic Anhydrase VIII and Effects of Missense Single Nucleotide Variations to Protein Structure and Function.Semantic proximity Read ↗

Carbonic anhydrase VIII as a regulator of intracellular calcium signaling: mechanistic insights and implications in human disease.Semantic proximity Read ↗

Comparative study of stability and activity of wild-type and mutant human carbonic anhydrase II enzymes using molecular dynamics and docking simulations.Semantic proximity Read ↗

Amino Acids as Building Blocks for Carbonic Anhydrase InhibitorsSemantic proximity Read ↗

Activation of α-, β-, γ- δ-, ζ- and η- class of carbonic anhydrases with amines and amino acids: a reviewSemantic proximity Read ↗

Crystal structure and chemical inhibition of essential schistosome host-interactive virulence factor carbonic anhydrase SmCASemantic proximity Read ↗

Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.Semantic proximity Read ↗

Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum—The η-carbonic anhydrasesSemantic proximity Read ↗

Structural insights into a thermostable variant of human carbonic anhydrase II.Semantic proximity Read ↗

1H, 15N and 13C resonance assignments of the S2A and H64A double mutant of human carbonic anhydrase II.Semantic proximity Read ↗

Cancer-Associated Carbonic Anhydrases and Their InhibitionSemantic proximity Read ↗

Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase .Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.