Article

Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors

2018-05-09

Abstract excerpt

Carbonic Anhydrases (CAs) are a superfamily of metalloenzymes widespread in all life kingdoms, classified into seven genetically different families (α-θ). These enzymes catalyse the reversible hydration of carbonic anhydride (CO2), generating bicarbonate (HCO3-) and protons (H+). Fifteen isoforms of human CA (hCA I-XV) have been isolated, their presence being fundamental for the regulation of many phys...

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Literature Corpus work: e7579f14-e654-5878-884b-e6227517fce0
DOI: 10.20944/preprints201805.0145.v1

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