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Article

Structural insights into a thermostable variant of human carbonic anhydrase II.

Protein science : a publication of the Protein Society - 1 Feb 2018

Kean Kelsey M, Porter Joseph J, Mehl Ryan A, Karplus P Andrew

Abstract excerpt

Carbonic anhydrase is an enzyme of interest for many biotechnological developments including carbon sequestration. These applications often require harsh conditions, so there is a need for the development of thermostable variants. One of the most thermostable human carbonic anhydrase II (HCAIIts) variants was patented in 2006. Here, we report the ultra-high resolution crystal structure of HCAIIts. The structural...

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Identifiers

PMID: 29139171
DOI: 10.1002/pro.3347
PMCID: PMC5775169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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