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T Cell Transcriptomes Describe Patient Subtypes in Systemic Lupus Erythematosus

6 Nov 2015

Abstract excerpt

BACKGROUND: T cells regulate the adaptive immune response and have altered function in autoimmunity. Systemic Lupus Erythematosus (SLE) has great diversity of presentation and treatment response. Peripheral blood component gene expression affords an efficient platform to investigate SLE immune dysfunction and help guide diagnostic biomarker development for patient stratification. METHODS: Gene expression in...

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PMID: 26544975
DOI: 10.1371/journal.pone.0141171

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