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Article

Leveraging pleiotropy for the improved treatment of psychiatric disorders

10 Oct 2024

Abstract excerpt

Over 90% of drug candidates fail in clinical trials, while it takes 10-15 years and one billion US dollars to develop a single successful drug. Drug development is more challenging for psychiatric disorders, where disease comorbidity and complex symptom profiles obscure the identification of causal mechanisms for therapeutic intervention. One promising approach for determining more suitable drug candidates in...

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PMID: 39390223
DOI: 10.1038/s41380-024-02771-7

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