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Article

Genetic correlation, pleiotropy, and causal associations between substance use and psychiatric disorder.

Psychological medicine - 1 Apr 2022

Jang Seon-Kyeong, Saunders Gretchen, Liu MengZhen, Jiang Yu, Liu Dajiang J, Vrieze Scott

Abstract excerpt

BACKGROUND: Substance use occurs at a high rate in persons with a psychiatric disorder. Genetically informative studies have the potential to elucidate the etiology of these phenomena. Recent developments in genome-wide association studies (GWAS) allow new avenues of investigation. METHOD: Using results of GWAS meta-analyses, we performed a factor analysis of the genetic correlation structure, a genome-wide...

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Share to Genetic Pleiotropy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32762793
DOI: 10.1017/S003329172000272X
PMCID: PMC8759148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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