Article
Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders.
Biological psychiatry - 1 Apr 2025
Strom Nora I, Halvorsen Matthew W, Grove Jakob, Ásbjörnsdóttir Bergrún, Luðvígsson Pétur, Thorarensen Ólafur, de Schipper Elles, Bäckmann Julia, Andrén Per, Tian Chao, Als Thomas Damm, Nissen Judith Becker, Meier Sandra M, Bybjerg-Grauholm Jonas, Hougaard David M, Werge Thomas, Børglum Anders D, Hinds David A, Rück Christian, Mataix-Cols David, Stefánsson Hreinn, Stefansson Kari, Crowley James J, Mattheisen Manuel
Abstract excerpt
BACKGROUND: Despite the significant personal and societal burden of tic disorders (TDs), treatment outcomes remain modest, necessitating a deeper understanding of their etiology. Family history is the biggest known risk factor, and identifying risk genes could accelerate progress in the field. METHODS: Expanding upon previous sample size limitations, we added 4800 new TD cases and 971,560 controls and conducted a...
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