Article
Mitochondrial DNA variant spectrum and the association with chronic tic disorders.
European journal of neurology - 1 Nov 2022
Jiang Peifang, Zhu Tao, Liu Jiajing, Tao Xiaohan, Xue Ziru, Tao Yiling, Chen Hongyu, Zeng Xiaojing, Zhu Weiyi, Shu Qiang, Yu Lan
Abstract excerpt
BACKGROUND AND PURPOSE: Tic disorders (TDs) are childhood onset neuropsychiatric disorders characterized by single or multiple sudden, rapid, recurrent, and motor tics and/or vocal tics. Several nuclear genes that are involved in mitochondrial functions suggest a potential role of mitochondria in TDs. METHODS: To evaluate the association of mitochondrial DNA (mtDNA) variants with TDs, we screened the whole...
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