Article
Genetic Susceptibility to Hidradenitis Suppurativa and Predisposition to Cardiometabolic Disease.
JAMA dermatology - 1 Jan 2025
Nielsen Valdemar Wendelboe, Bundgaard Vad Oliver, Holgersen Nikolaj, Paludan-Müller Christian, Meseguer Monfort Laia, Beyer Astrid Filt, Jemec Gregor Borut Ernst, Kjærsgaard Andersen Rune, Egeberg Alexander, Thyssen Jacob P, Svendsen Jesper Hastrup, Rosenø Nana Aviaaja Lippert, Hansen Peter Riis, Thomsen Simon Francis, Salling Olesen Morten
Abstract excerpt
Importance: Hidradenitis suppurativa (HS) is associated with an increased prevalence of cardiovascular diseases compared with the general population. Any association between polygenic risk for HS, risk of incident cardiometabolic outcomes, and the plasma proteome is unclear. Objective: To investigate the genetic correlation between HS and cardiometabolic disease. Design, Setting, and Participants: This cohort...
Read the complete abstract on PubMedTopics
- Humans
- Hidradenitis Suppurativa
- Female
- Male
- Genetic Predisposition to Disease