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Article

Integrated Proteogenomics and Single-Cell Transcriptomics Prioritize Putative Protective Plasma Proteins for Hidradenitis Suppurativa.

Experimental dermatology - 1 Jul 2026

Cheng Yuzhe, Ma Jingyi, Niu Jun

Abstract excerpt

Translating hidradenitis suppurativa (HS) genetic susceptibility into actionable targets remains challenging, as most genome-wide association study loci lie in non-coding regions and tissue-level transcriptomics cannot easily distinguish causal drivers from secondary inflammation. In this study, we aimed to prioritize plasma proteins whose genetically predicted levels are causally associated with HS risk and to...

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Source

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Identifiers

PMID: 42499219
DOI: 10.1111/exd.70332
PMCID: PMC13400889

Genes

APOD
FCRL2
TNFRSF6B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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