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Identification of Novel Genetic Risk Variants Associated with Hidradenitis Suppurativa in an Exome Sequencing Cohort of 92,455 Individuals.

Dermatology (Basel, Switzerland) - 1 Jan 2024

Metpally Raghu P, Vishweswaraiah Sangeetha, Krishnamurthy Sarathbabu, Saiyed Nazia, Stahl Richard C, Golden Alicia, Denisenko Andrew, Staples Jeffrey, Gonzaga-Jauregui Claudia, Carey David J, Bechara Falk, Jemec Gregor B E, Williams Heinric, Radhakrishna Uppala

Abstract excerpt

INTRODUCTION: Hidradenitis suppurativa (HS) is a prevalent and persistent inflammatory skin disorder, lacking a known cure or effective biomarkers for early diagnosis at present. The genetic determinants of HS have not been fully documented, but it is believed to result from a combination of genetic and environmental factors. METHODS: To identify relevant HS gene variants in sporadic HS patients, this study...

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PMID: 39396498
DOI: 10.1159/000540359

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