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Article

Pancreatic cancer evolution and heterogeneity: integrating omics and clinical data.

Nature reviews. Cancer - 1 Mar 2022

Connor Ashton A, Gallinger Steven

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC), already among the deadliest epithelial malignancies, is rising in both incidence and contribution to overall cancer deaths. Decades of research have improved our understanding of PDAC carcinogenesis, including characterizing germline predisposition, the cell of origin, precursor lesions, the sequence of genetic alterations, including simple and structural alterations,...

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Share to Carcinoma, Pancreatic Ductal
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34789870
DOI: 10.1038/s41568-021-00418-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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