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Neurofilament light chain as a biomarker for hereditary ATTR amyloidosis − correlation between neurofilament light chain and nerve conduction study

1 Oct 2024

Abstract excerpt

BACKGROUND: Neurofilament light chain (NfL) is a biomarker of neuronal injury in hereditary ATTR (ATTRv) amyloidosis. However, the correlation between NfL and nerve conduction study (NCS), the standard test for ATTRv neuropathy, has not been investigated. OBJECTIVE: Elucidate the correlation between NfL and NCS parameters. METHODS: 227 serum NfL measurements were performed in 45 ATTRv patients, 5 asymptomatic...

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PMID: 39377666
DOI: 10.1080/13506129.2024.2409760

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