Integrating Clinical and Genetic Analysis of Perineural Invasion in Head and Neck Squamous Cell Carcinoma

Abstract excerpt

Introduction Perineural invasion (PNI), a key pathological feature of head and neck squamous cell carcinoma (HNSCC), predicts poor survival. However, the associated clinical characteristics remain uncertain, and the molecular mechanisms are largely unknown. Materials and methods HNSCC gene expression and corresponding clinical data were downloaded from the Cancer Genome Atlas (TCGA). Prognostic subgroup analysis...

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