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Article

Molecular Landscape of Pelvic Organ Prolapse Provides Insights into Disease Etiology

23 Mar 2023

Abstract excerpt

Pelvic organ prolapse (POP) represents a major health care burden in women, but its underlying pathophysiological mechanisms have not been elucidated. We first used a case-control design to perform an exome chip study in 526 women with POP and 960 control women to identify single nucleotide variants (SNVs) associated with the disease. We then integrated the functional interactions between the POP candidate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37047060
DOI: 10.3390/ijms24076087

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