Article
Identification of six loci associated with pelvic organ prolapse using genome-wide association analysis.
Obstetrics and gynecology - 1 Dec 2011
Allen-Brady Kristina, Cannon-Albright Lisa, Farnham James M, Teerlink Craig, Vierhout Mark E, van Kempen Léon C L, Kluivers Kirsten B, Norton Peggy A
Abstract excerpt
OBJECTIVE: There is evidence that both environmental and genetic factors contribute to pelvic organ prolapse. We conducted a genome-wide association study to investigate whether common genetic variants modify the risk of pelvic organ prolapse. METHODS: We recruited women who had been evaluated and treated for pelvic organ prolapse at the University of Utah from 1996 to 2008 and their affected female relatives....
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