Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ETV4‑mediated transcriptional activation of SLC12A5 exacerbates ferroptosis resistance and glucose metabolism reprogramming in breast cancer cells

26 Sept 2024

Abstract excerpt

Solute carrier family 12 member 5 (SLC12A5) is an oncogene in numerous types of cancer, however its function in breast cancer (BC) remains elusive.ETS translocation variant 4 (ETV4) promotes BC.Therefore, the present study aimed to elucidate the role of SLC12A5 in ferroptosis and glucose metabolism in BC cells as well as to understand the underlying mechanism.Analysis of data from the UALCAN database demonstrated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39370816
DOI: 10.3892/mmr.2024.13341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ETV4‑mediated transcriptional activation of SLC12A5 exacerbates ferroptosis resistance and glucose metabolism reprogramming in breast cancer cellsPMID 39370816Read ↗

Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapySemantic proximity Read ↗

Exploring Aerobic Energy Metabolism in Breast Cancer: A Mutational Profile of Glycolysis and Oxidative Phosphorylation.Semantic proximity Read ↗

CtBP Promoted P4HB Mediates SLC7A11 Maturation to Confer Ferroptosis Resistance in Triple-Negative Breast CancerSemantic proximity Read ↗

ALOX5 deficiency contributes to bladder cancer progression by mediating ferroptosis escapeSemantic proximity Read ↗

miR-526b dysregulates glucose metabolism via the COX2/EP4 pathwaySemantic proximity Read ↗

ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosisSemantic proximity Read ↗

GluOC Induced SLC7A11 and SLC38A1 to Activate Redox Processes and Resist Ferroptosis in TNBCSemantic proximity Read ↗

The Tissue Expression of MCT3, MCT8, and MCT9 Genes in Women with Breast CancerSemantic proximity Read ↗

Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancerSemantic proximity Read ↗

Overexpressed VDAC1 in breast cancer as a novel prognostic biomarker and correlates with immune infiltratesSemantic proximity Read ↗

Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancerSemantic proximity Read ↗

GLUT1 inhibition blocks growth of RB1-positive Triple Negative Breast CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.