Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis

13 Jan 2023

Abstract excerpt

Introduction: Relapse of breast cancer is one of the key obstacles to successful treatment. Previously we have shown that low expression of ELOVL5 and IGFBP6 genes in breast cancer tissue corresponded to poor prognosis. ELOVL5 participates directly in the elongation of polyunsaturated fatty acids (PUFAs) that are considered to play an important role in cancer cell metabolism. Thus, in this work we studied the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36714261
DOI: 10.3389/fmolb.2023.1075704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosisPMID 36714261Read ↗

ETV4‑mediated transcriptional activation of SLC12A5 exacerbates ferroptosis resistance and glucose metabolism reprogramming in breast cancer cellsSemantic proximity Read ↗

FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancerSemantic proximity Read ↗

FADS1/2-mediated lipid metabolic reprogramming drives ferroptosis sensitivity in triple-negative breast cancerSemantic proximity Read ↗

SCD5 Expression Correlates with Prognosis and Response to Neoadjuvant Chemotherapy in Breast CancerSemantic proximity Read ↗

Omega-3 Docosahexaenoic Acid as a Promising Inducer of Ferroptosis: Dynamics of Action in Prostate and Colorectal Cancer ModelsSemantic proximity Read ↗

ESR1-Activating Mutations Confer Metabolic Vulnerabilities in ER+ Breast Cancer.Semantic proximity Read ↗

Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasisSemantic proximity Read ↗

EGR1 Promotes Erastin-induced Ferroptosis Through Activating Nrf2-HMOX1 Signaling Pathway in Breast Cancer CellsSemantic proximity Read ↗

Lipid metabolic reprogramming drives triglyceride storage and variable sensitivity to FASN inhibition in endocrine-resistant breast cancer cellsSemantic proximity Read ↗

Novel (1S,3R)-RSL3-Encapsulated Polyunsaturated Fatty Acid Rich Liposomes Sensitise Multiple Myeloma Cells to Ferroptosis-Mediated Cell DeathSemantic proximity Read ↗

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer.Semantic proximity Read ↗

Docosahexaenoic acid intake decreases proliferation, increases apoptosis and decreases the invasive potential of the human breast carcinoma cell line MDA-MB-231.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.