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Article

Exploring Aerobic Energy Metabolism in Breast Cancer: A Mutational Profile of Glycolysis and Oxidative Phosphorylation.

International journal of molecular sciences - 23 Nov 2024

Oliveira Ricardo Cunha de, Cavalcante Giovanna C, Soares-Souza Giordano B

Abstract excerpt

Energy metabolism is a fundamental aspect of the aggressiveness and invasiveness of breast cancer (BC), the neoplasm that most affects women worldwide. Nonetheless, the impact of genetic somatic mutations on glycolysis and oxidative phosphorylation (OXPHOS) genes in BC remains unclear. To fill these gaps, the mutational profiles of 205 screened genes related to glycolysis and OXPHOS in 968 individuals with BC...

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Identifiers

PMID: 39684297
DOI: 10.3390/ijms252312585
PMCID: PMC11641591

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