Article

Pure Apocrine Intraductal Carcinoma of Salivary Glands: Reassessment of Molecular Underpinnings and Behavior

2024-03-29

Abstract excerpt

Intraductal carcinoma (IDC) of the salivary glands is a confounding entity, our understanding of which continues to evolve. At least four forms have been elucidated based on histomorphology, immunophenotype, and molecular profile: 1) intercalated duct-like, S100/SOX10 + with frequent NCOA4 RET fusions; 2) oncocytic, S100/SOX10 + with TRIM33 RET , NCOA4 RET , and BRAF V600E; 3) apocrine, AR + with PI3 kinase pathwa...

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Literature Corpus work: 3e7f225f-b776-547e-b117-ceb0b0555de4
DOI: 10.21203/rs.3.rs-4158833/v1

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