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Article

CXCR3-CXCL11 Signaling Restricts Angiogenesis and Promotes Pericyte Recruitment.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2024

Lee Jihui, Goeckel Megan E, Levitas Allison, Colijn Sarah, Shin Jimann, Hindes Anna, Mun Geonyoung, Burton Zarek, Chintalapati Bharadwaj, Yin Ying, Abello Javier, Solnica-Krezel Lilianna, Stratman Amber N

Abstract excerpt

BACKGROUND: Endothelial cell (EC)-pericyte interactions are known to remodel in response to hemodynamic forces; yet there is a lack of mechanistic understanding of the signaling pathways that underlie these events. Here, we have identified a novel signaling network regulated by blood flow in ECs-the chemokine receptor CXCR3 (CXC motif chemokine receptor 3) and one of its ligands, CXCL11 (CXC motif chemokine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39360413
DOI: 10.1161/ATVBAHA.124.321434
PMCID: PMC11594002

Genes

CXCR3
CXCL11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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