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Article

Associations of combined accelerated biological aging and genetic susceptibility with incident dementia: a prospective study in the UK Biobank.

BMC medicine - 30 Sept 2024

Ye Zirong, Lang Haoxiang, Xie Zishan, Duan Siyu, Peng Bihao, Chen Xiaochun, Fang Ya, Xin Jiawei

Abstract excerpt

BACKGROUND: Accelerated biological aging has been verified to be a critical risk factor for a number of age-related diseases, but its role in dementia remained unclear. Whether it modified the effects of genetic factors was also unknown. This study evaluated the associations between accelerated biological aging and dementia and the moderating role of accelerated biological aging in the genetic susceptibility to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39350213
DOI: 10.1186/s12916-024-03640-4
PMCID: PMC11443929

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