Article
Association of autosomal mosaic chromosomal alterations with risk of bladder cancer in Chinese adults: a prospective cohort study.
Cell death & disease - 30 Sept 2024
Song Mingyu, Han Yuting, Zhao Yuxuan, Lv Jun, Yu Canqing, Pei Pei, Yang Ling, Millwood Iona Y, Walters Robin G, Chen Yiping, Du Huaidong, Yang Xiaoming, Yao Wei, Chen Junshi, Chen Zhengming, Genovese Giulio, Terao Chikashi, Li Liming, Sun Dianjianyi
Abstract excerpt
Little is known about the prospective association between autosomal mosaic chromosomal alterations (mCAs), a group of large-scale somatic mutations on autosomes, and bladder cancer. Here we utilized data from 99,877 participants who were free of physician-diagnosed cancer at baseline (2004-2008) of the China Kadoorie Biobank to estimate the associations between autosomal mCAs and bladder cancer (ICD-10: C67). A...
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