Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor Predisposing Post-Zygotic Chromosomal Alterations in Bladder Cancer—Insights from Histologically Normal Urothelium

27 Feb 2024

Abstract excerpt

Bladder urothelial carcinoma (BLCA) is the 10th most common cancer with a low survival rate and strong male bias. We studied the field cancerization in BLCA using multi-sample- and multi-tissue-per-patient protocol for sensitive detection of autosomal post-zygotic chromosomal alterations and loss of chromosome Y (LOY). We analysed 277 samples of histologically normal urothelium, 145 tumors and 63 blood samples...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
Share to Urinary and Genital Oncology Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38473323
DOI: 10.3390/cancers16050961

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor Predisposing Post-Zygotic Chromosomal Alterations in Bladder Cancer—Insights from Histologically Normal UrotheliumPMID 38473323Read ↗

Association of autosomal mosaic chromosomal alterations with risk of bladder cancer in Chinese adults: a prospective cohort study.Semantic proximity Read ↗

Genomic complexity of urothelial bladder cancer revealed in urinary cfDNASemantic proximity Read ↗

Mosaic uniparental disomies and aneuploidies as large structural variants of the human genome.Semantic proximity Read ↗

Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.Semantic proximity Read ↗

Clinical and genomic profiling of early-onset bladder cancer identifies key alterations and therapeutic targetsSemantic proximity Read ↗

Noninvasive Detection of Urothelial Carcinoma by Cost-effective Low-coverage Whole-genome Sequencing from Urine-Exfoliated Cell DNA.Semantic proximity Read ↗

A pan-tissue survey of mosaic chromosomal alterations in 948 individuals.Semantic proximity Read ↗

The Evolving Molecular Landscape and Actionable Alterations in Urologic Cancers.Semantic proximity Read ↗

Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancersSemantic proximity Read ↗

Mutation signatures to Pan-Cancer Atlas: Investigation of the genomic landscape of muscle-invasive bladder cancer.Semantic proximity Read ↗

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.Semantic proximity Read ↗

Racial differences in genomic features and new trans-ancestry prognosis subtypes in bladder cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.