Article
Two distinct phenotypes of calcium oxalate stone formers could imply different long-term risks for renal function.
Urolithiasis - 28 Sept 2024
Williams James C, Bowen William S, Lingeman James E, Rivera Marcelino, Worcester Elaine M, El-Achkar Tarek M
Abstract excerpt
Endoscopic and biopsy findings have identified two distinct phenotypes among individuals with calcium oxalate (CaOx) kidney stones. The first type has normal renal papillae but shows interstitial mineral deposition, known as Randall's plaque. The other phenotype presents with collecting duct plugging and a higher incidence of loss of papilla tissue mass. With Randall's plaque, renal papilla injury involves the...
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