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Article

Aspirin may be more suitable for patients with major depression: Evidence from two-sample Mendelian randomization analysis.

Journal of psychopharmacology (Oxford, England) - 1 Dec 2024

Zhu Haohao, Qu Yucai, Zhou Qin, Du Zhiqiang, Zhou Zhenhe, Jiang Ying

Abstract excerpt

OBJECTIVE: Utilizing two-sample Mendelian randomization (TSMR) analysis, this study aims to explore the potential bidirectional causal relationship between common nonsteroidal anti-inflammatory drugs (paracetamol, ibuprofen, aspirin) and major depression (MD) from a genetic standpoint. METHODS: We employed summarized data from a Genome-Wide Association Study (GWAS) of European populations. The inverse variance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39319547
DOI: 10.1177/02698811241282613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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