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Article

Impact of age on genomic alterations and the tumor immune microenvironment in papillary thyroid cancer.

Endocrine-related cancer - 1 Dec 2024

Liddy Dominique D, Zhang Zhongyue, Shirlekar Kalyanee, He Zhongping, Herremans Kelly M, Han Song, Brant Jason O, Moore Francis D, Hughes Steven J, Shirali Aditya S

Abstract excerpt

Differentiated thyroid cancer in older adults has been linked to alterations in the mutational landscape and tumor immune cell infiltration that create a tumor-permissive microenvironment. We sought to determine the impact of age on genomic alterations and immune cell composition in papillary thyroid cancer (PTC). Genomic alterations, immune cell composition, and clinical data were obtained using The Cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39315956
DOI: 10.1530/ERC-23-0341
PMCID: PMC11608430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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