Article
Promoter mutation-independent TERT expression is related to the immune-enriched milieu in papillary thyroid cancer.
Endocrine-related cancer - 1 Nov 2024
Seo Dong Hyun, Lee Seul Gi, Choi Soon Min, Kim Ha Yan, Park Sunmi, Jung Sang Geun, Jo Young Suk, Lee Jandee
Abstract excerpt
Telomerase reverse transcriptase promoter mutation (pTERT MT) promotes human carcinogenesis via aberrant expression of telomerase reverse transcriptase (TERT). However, the tumorigenic impact of TERT expression independent of pTERT MT remains unclear despite numerous mechanisms of TERT being suggested. To tackle this issue, we employed comprehensive bioinformatics to assess biological variations noticed among...
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