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Article

Evolution of antigenic diversity in the tick‐transmitted bacterium Borrelia afzelii: a role for host specialization?

27 Mar 2017

Abstract excerpt

Antigenic diversity in pathogenic microbes can be a result of at least three different processes: diversifying selection by acquired immunity, host-pathogen coevolution and/or host specialization. Here, we investigate whether host specialization drives diversity at ospC (which encodes an immunodominant surface protein) in the tick-transmitted bacterium Borrelia afzelii. We determined prevalence and infection...

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PMID: 28345277
DOI: 10.1111/jeb.13075

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