Article
Phosphorylation mapping of laminin γ1-chain: Kinases, functional interaction sequences, and phosphorylationinterfering cancer mutations.
Journal of biosciences - 1 Jan 2024
Galliou Panagiota-Angeliki, Verrou Kleio-Maria, Papanikolaou Nikolaos A, Koliakos George
Abstract excerpt
We computationally predicted all phosphorylation sites in the sequence of the human laminin γ1-chain (LAMC1), and computationally identified, for the first time, all kinases for experimentally observed phosphorylated residues of the LAMC1 and all missense deleterious LAMC1 mutations found in different cancer types that interfere with LAMC1 phosphorylation. Also, we mapped the above data to all the biologically...
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