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Article

Somatic and germline mutations in endometrial cancer.

Journal of medicine and life - 1 Jun 2024

Botea Robert, Piron-Dumitrascu Madalina, Georgescu Tiberiu Augustin, Bohiltea Camil Laurentiu, Voinea Silviu Cristian, Varlas Valentin Nicolae, Iacoban Simona Raluca, Suciu Nicolae

Abstract excerpt

Endometrial cancer is a complex disease influenced by both somatic and germline mutations. While individual mutations in genes such as PTEN, PIK3CA, and members of the DNA mismatch repair (MMR) system have been extensively studied, comprehensive analyses comparing somatic and germline mutations within the same cohort are limited. This study compares these mutations using whole exome sequencing (WES) data from...

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Source

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Identifiers

PMID: 39296440
DOI: 10.25122/jml-2024-0313
PMCID: PMC11407495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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