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Single‐cell RNA sequencing reveals the heterogeneity of MYH11 + tumour‐associated fibroblasts between left‐sided and right‐sided colorectal cancer

1 Sept 2024

Abstract excerpt

Colorectal cancer (CRC) exhibits considerable heterogeneity on tumour location. However, there is still a lack of comprehensive annotation regarding the characteristics and differences between the left-sided (L-CRC) and right-sided (R-CRC) CRC. Here, we performed single-cell RNA sequencing (scRNA-seq) on immune and stromal cells from 12 L-CRC and 10 R-CRC patients. We found that L-CRC exhibited stronger tumour...

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PMID: 39294858
DOI: 10.1111/jcmm.70102

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