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Genetic Variation and Mendelian Randomization Approaches.

Advances in experimental medicine and biology - 1 Jan 2022

Yazdanpanah Mojgan, Yazdanpanah Nahid, Manousaki Despoina

Abstract excerpt

While genome-wide association studies (GWAS) on levels of nuclear receptors are sparse, the genetics of ligands of these receptors (steroid hormones, thyroid hormones, and liposoluble vitamins) have been extensively studied in GWAS of predominantly European populations. Hundreds of genetic variants across the genome have been associated with serum levels of nuclear receptor ligands, shedding light on the...

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PMID: 36107328
DOI: 10.1007/978-3-031-11836-4_19

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