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Article

Investigating the shared genetic basis of inflammatory bowel disease and systemic lupus erythematosus using genetic overlap analysis.

BMC genomics - 16 Sept 2024

Yuan Weichao, Luo Qinghua, Wu Na

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) and systemic lupus erythematosus (SLE) are autoimmune diseases that often coexist clinically. This phenomenon might be due to shared genetic components. METHODS: Genome-wide association study (GWAS) data for IBD and SLE were analyzed to determine both global and local genetic correlations using three methodologies: linkage disequilibrium score regression (LDSC),...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inflammatory Bowel Diseases

Share to Linkage Disequilibrium

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 39285290
DOI: 10.1186/s12864-024-10787-0
PMCID: PMC11406968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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