Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Investigating the shared genetic basis of inflammatory bowel disease and systemic lupus erythematosus using genetic overlap analysis.

BMC genomics - 16 Sept 2024

Yuan Weichao, Luo Qinghua, Wu Na

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) and systemic lupus erythematosus (SLE) are autoimmune diseases that often coexist clinically. This phenomenon might be due to shared genetic components. METHODS: Genome-wide association study (GWAS) data for IBD and SLE were analyzed to determine both global and local genetic correlations using three methodologies: linkage disequilibrium score regression (LDSC),...

Topics

Join the communities discussing this publication.

Genetic Predisposition to Disease
Genome-Wide Association Study
Inflammatory Bowel Diseases
Linkage Disequilibrium
Lupus Erythematosus, Systemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 39285290
DOI: 10.1186/s12864-024-10787-0
PMCID: PMC11406968

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating the shared genetic basis of inflammatory bowel disease and systemic lupus erythematosus using genetic overlap analysis.PMID 39285290Read ↗

Uncovering shared genetic features between inflammatory bowel disease and systemic lupus erythematosusSemantic proximity Read ↗

Genome-wide cross-trait analysis reveals shared genetic architecture between inflammatory bowel disease and ankylosing spondylitis.Semantic proximity Read ↗

A multilevel analysis of the genetic association between inflammatory bowel disease and primary sclerosing cholangitis.Semantic proximity Read ↗

Inflammatory bowel disease and rheumatoid arthritis share a common genetic structure.Semantic proximity Read ↗

Cross-trait mapping of shared susceptibility across inflammatory bowel disease and spondyloarthropathies.Semantic proximity Read ↗

A multilayered genetic structure analysis between inflammatory bowel disease and bone density/osteoporosis.Semantic proximity Read ↗

Evidence for the gut‐skin axis: Common genetic structures in inflammatory bowel disease and psoriasisSemantic proximity Read ↗

Shared Genetic Basis Between Systemic Lupus Erythematosus and Inflammatory Bowel Disease in East Asian Ancestry: A Genome-Wide Cross-trait Analysis.Semantic proximity Read ↗

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.Semantic proximity Read ↗

Integrative analysis of genetic and cellular interactions connecting inflammatory bowel disease and primary biliary cholangitis.Semantic proximity Read ↗

Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases.Semantic proximity Read ↗

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.