Article
Blood metabolites, neurocognition and psychiatric disorders: a Mendelian randomization analysis to investigate causal pathways.
Translational psychiatry - 16 Sept 2024
Guo Jing, Yang Ping, Wang Jia-Hao, Tang Shi-Hao, Han Ji-Zhou, Yao Shi, Yu Ke, Liu Cong-Cong, Dong Shan-Shan, Zhang Kun, Duan Yuan-Yuan, Yang Tie-Lin, Guo Yan
Abstract excerpt
BACKGROUND: Neurocognitive dysfunction is observationally associated with the risk of psychiatric disorders. Blood metabolites, which are readily accessible, may become highly promising biomarkers for brain disorders. However, the causal role of blood metabolites in neurocognitive function, and the biological pathways underlying their association with psychiatric disorders remain unclear. METHODS: To explore...
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