Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization.

BMC medicine - 8 Aug 2023

Woolf Benjamin, Cronjé Héléne T, Zagkos Loukas, Burgess Stephen, Gill Dipender, Larsson Susanna C

Abstract excerpt

BACKGROUND: Caffeine exposure modifies the turnover of monoamine neurotransmitters, which play a role in several neuropsychiatric disorders. We conducted a Mendelian randomization study to investigate whether higher plasma caffeine levels are causally associated with the risk of anorexia nervosa, bipolar disorder, major depressive disorder (MDD), and schizophrenia. METHODS: Summary-level data on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caffeine
Share to Causality
Share to Coffee research and impacts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Genetic Associations and Epidemiology

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 37553644
DOI: 10.1186/s12916-023-03008-0
PMCID: PMC10408049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization.PMID 37553644Read ↗

Blood metabolites, neurocognition and psychiatric disorders: a Mendelian randomization analysis to investigate causal pathways.Semantic proximity Read ↗

Discovery of Urinary Metabolite Biomarkers of Psychiatric Disorders Using Two-Sample Mendelian RandomizationSemantic proximity Read ↗

Unravelling the role of alanine in mental disorders: a Mendelian randomisation study.Semantic proximity Read ↗

Mendelian Randomization Studies of Coffee and Caffeine ConsumptionSemantic proximity Read ↗

Causal relationship of polyunsaturated fatty acids with mental disorders: a systematic review and meta-analysisSemantic proximity Read ↗

Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization.Semantic proximity Read ↗

Bidirectional causality between micronutrients and mental illness: Mendelian randomization studies.Semantic proximity Read ↗

The Causal Effects of Insomnia on Bipolar Disorder, Depression, and Schizophrenia: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

Neuropsychiatric Disorders and Constipation: Unraveling Causal Links Through Genetic Analysis.Semantic proximity Read ↗

Obesity influencing circulating levels of nutrients: Evidence from Mendelian randomization study.Semantic proximity Read ↗

Genetic evidence for the causal relations between metabolic syndrome and psychiatric disorders: a Mendelian randomization studySemantic proximity Read ↗

Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization AnalysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.