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Article

Assessing the causal association between human blood metabolites and the risk of epilepsy.

Journal of translational medicine - 30 Sept 2022

Cai Jiahao, Li Xiaoyu, Wu Shangbin, Tian Yang, Zhang Yani, Wei Zixin, Jin Zixiang, Li Xiaojing, Chen Xiong, Chen Wen-Xiong

Abstract excerpt

BACKGROUND: Metabolic disturbance has been reported in patients with epilepsy. Still, the evidence about the causal role of metabolites in facilitating or preventing epilepsy is lacking. Systematically investigating the causality between blood metabolites and epilepsy would help provide novel targets for epilepsy screening and prevention. METHODS: We conducted two-sample Mendelian randomization (MR) analysis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36180952
DOI: 10.1186/s12967-022-03648-5
PMCID: PMC9524049

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