Article
Exploring Genetic Interactions in Colombian Women with Polycystic Ovarian Syndrome: A Study on SNP-SNP Associations.
International journal of molecular sciences - 25 Aug 2024
Alarcón-Granados Maria Camila, Camargo-Villalba Gloria Eugenia, Forero-Castro Maribel
Abstract excerpt
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder with high prevalence in women around the world. The identification of single-nucleotide polymorphisms (SNPs) through genome-wide association studies has classified it as a polygenic disease. Most studies have independently evaluated the contribution of each SNP to the risk of PCOS. Few studies have assessed the effect of epistasis among the...
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