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Mutational Landscape Screening Through Comprehensive In Silico Analysis for Polycystic Ovarian Syndrome-Related Genes.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Feb 2022

Dhar Shrinjana, Mridha Saptarshi, Bhattacharjee Pritha

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a multifactorial endocrinopathy of indistinguishable etiopathogenesis that is liable to entail genetic and environmental machinery synergistically interacting with its phenotypic expression. It has been hypothesized that the environment secondarily interacts with genes to define the quantifiable phenotype in a primary, genetically determined, hyper-androgenic ovarian defect....

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PMID: 34697776
DOI: 10.1007/s43032-021-00752-7

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