Article
Genetics of polycystic ovary syndrome.
Expert review of molecular diagnostics - 1 Jul 2017
Mykhalchenko Kateryna, Lizneva Daria, Trofimova Tatiana, Walker Walidah, Suturina Larisa, Diamond Michael P, Azziz Ricardo
Abstract excerpt
INTRODUCTION: Polycystic ovary syndrome (PCOS) is a hormonal and metabolic disorder affecting 5 to 20% of reproductive-aged women worldwide that results in androgen excess, menstrual dysfunction and oligo-ovulatory subfertility, with increased risks for type 2 diabetes, endometrial adenocarcinoma, and potentially vascular disease, among other morbidities. PCOS is a complex genetic trait with strong heritability...
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