Article
Causal relationship between circulating glutamine levels and idiopathic pulmonary fibrosis: a two-sample mendelian randomization study.
BMC pulmonary medicine - 13 Sept 2024
Xu Tao, Liu Chengyu, Ning Xuecong, Gao Zhiguo, Li Aimin, Wang Shengyun, Leng Lina, Kong Pinpin, Liu Pengshuai, Zhang Shusen, Zhang Ping
Abstract excerpt
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and debilitating respiratory disease with a median survival of less than 5 years. In recent years, glutamine has been reported to be involved in the regulation of collagen deposition and cell proliferation in fibroblasts, thereby influencing the progression of IPF. However, the relationships between glutamine and the incidence, progression, and...
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