Article
Genetic association of circulating C-reactive protein levels with idiopathic pulmonary fibrosis: a two-sample Mendelian randomization study.
Respiratory research - 9 Jan 2023
Zhang Kun, Li Anqi, Zhou Jiejun, Zhang Chaoguo, Chen Mingwei
Abstract excerpt
BACKGROUND: Several observational studies have found that idiopathic pulmonary fibrosis (IPF) is often accompanied by elevated circulating C-reactive protein (CRP) levels. However, the causal relationship between them remains to be determined. Therefore, our study aimed to explore the causal effect of circulating CRP levels on IPF risk by the two-sample Mendelian randomization (MR) analysis. METHODS: We analyzed...
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